徐勇（英文）

Xu Yong

1989-09-13

Email address: yxu1615@suda.edu.cn

gain distinction ：

National-level Young Talent (Outstanding Young Talent – Overseas)

Distinguished Professor of Jiangsu Province; Leading Talent in Gusu District, Suzhou City; Deputy Director of Science and Technology Department of Jiangsu Province

Distinguished Professor at Soochow University's Dongwu School; Top Talent

Professor at the Institute of Orthopedics, Soochow University; Doctoral Supervisor; Postdoctoral Collaborative Supervisor; Principal Investigator (PI)

Double-appointed Professor at the First Affiliated Hospital and the Third Affiliated Hospital of Soochow University

Double-Appointed Professor at Nanjing Hospital of Traditional Chinese Medicine

Postdoctoral Supervisor at the Biomedical Innovation Cluster of Suzhou Industrial Park

Member of the Biopharmaceutical Committee of the Jiangsu Provincial Association of Young Scientists and Technologists

Special Expert appointed by the Expert Committee of the Jiangsu Provincial Overseas Chinese Federation

Expert at the Think Tank of the Overseas Chinese Innovation Alliance under the Suzhou Overseas Chinese Federation

Standing Committee Member of the Tissue Repair and Immunology Committee, Jiangsu Provincial Society of Immunology

Chairperson of the Second Branch of the Chinese Peasant and Workers Democratic Party at Soochow University

Co-founder and Chief Technology Officer of Suzhou Xianjue New Materials Technology Co., Ltd.

study experience ：

September 2008 – June 2012: China, Bachelor's degree in Biotechnology, Nantong University

July 2012 – July 2014: China, Master's degree, Sun Yat-sen University, Biomedical Engineering

October 2014 – October 2019: Germany; Doctorate; Technical University of Dresden; Bone Tissue Engineering and Regenerative Medicine

work experience ：

May 2019 – June 2022: Postdoctoral researcher at Technische Universität Dresden, Germany

July 2022 – present : Professor, China Suzhou University           

research area ：

1. Exploration of the Mechanisms of Immune Microenvironment Regulation and Mitochondrial Metabolism in Bone/Muscle Regeneration and Repair

2. Integrated Industry-Academia-Research-Medical Approach for Development and Translation of Orthopedic Medical Devices for Refractory Musculoskeletal Injuries

3. Synthetic Biology-Driven Development of Active Biomaterial Devices for the Treatment and Regeneration of Intervertebral Disc Degeneration: Fundamental Principles and Translational Applications

4. Translational medical research on AI-driven functional dressings or implantable devices for sports system injuries

Self-introduction ：

From 2014 to 2022, I obtained my doctoral degree from the prestigious German university, the Technical University of Dresden, and conducted postdoctoral research in a leading German research team specializing in biomedical and biomaterial polymer materials under the guidance of renowned European biomaterial expert Professor Yixin Zhang and Professor Carsten Werner, member of the German Academy of Engineering. In recent years, my research has consistently focused on the key scientific question of "exploring therapeutic mechanisms for bone diseases—modulating the ECM microenvironment—and applying these findings to bone tissue repair." As first or corresponding author, I have published 30 papers in internationally renowned SCI-indexed journals such as Nature Communications, Advanced Science, Biomaterials, and Journal of Controlled Release.

Upon returning to China in July 2022, he has led multiple research projects funded by the National Natural Science Foundation of China, the Jiangsu Provincial Natural Science Foundation, as well as national, provincial, and municipal talent programs in Suzhou. He has been granted 10 domestic patents and 3 international patents in the United States and Europe. The related research achievements have been successfully commercialized. He received funding under Germany's Federal Ministry of Education and Research's research transfer incubation program "EXIST-Forschungstransfer" (with a grant amount of €2 million) and established the biotechnology company "denovo MATRIX" in Germany in 2019. The company's products are now commercially available, providing safe, stable, and efficient stem cell expansion and directed differentiation matrix surface products for numerous pharmaceutical and stem cell companies.

Current research efforts are primarily focused on "the regulatory role of the extracellular matrix in the regenerative repair mechanisms of refractory injuries in the musculoskeletal system," aiming to elucidate the molecular mechanisms by which the extracellular matrix promotes tissue regeneration through modulation of mitochondrial energy metabolism, immune microenvironment, and intracellular/extracellular redox balance, thereby identifying novel therapeutic targets for musculoskeletal injury repair. Relevant findings have been commercialized in Suzhou, fostering collaborative innovation among industry, academia, research institutions, and healthcare sectors in the development of innovative biomaterials and medical devices, and providing new insights and technological pathways for tissue regeneration and organ manufacturing in the musculoskeletal system. In January 2023, Xianjue New Materials Technology Co., Ltd. (https://xjmatrix.com/) was co-founded at BioBay in Suzhou Industrial Park with a registered capital of RMB 10 million, where the researcher serves as co-founder and Chief Technology Officer, specializing in the research, development, and commercialization of innovative biomaterials and medical devices.

project ：

Representative works from the past five years

[1] Yong Xu, Rebecca Rothe, Dagmar Voigt, Sandra Hauser, Meiying Cui, Takuya Miyagawa, Michelle Patino Gaillez, Thomas Kurth, Martin Bornhauser, Jens Pietzsch*, and Yixin Zhang*. Convergent synthesis of diverse reversible networks yields conductive hydrogel adhesives containing liquid metals. Nature Communications, 12(1),1–19 (2021). (First author; IF 17.694; Category: Zone I)

[2] Yilin Yang, Jiangbo Guo, Haifei Cao, Xin Tian, Hao Shen, Junjie Niu, Huilin Yang*, Qin Shi*, Yong Xu*. "Seeds-and-Soil Inspired Hydrogel Microspheres: A Dual-Action Antioxidant and Cellular Therapy for Reversing Intervertebral Disc Degeneration." Biomaterials (2025):123326. (Last corresponding author; IF = 12; Category: Zone I)

[3] Xin Tian, Yan Miao, Hao Liu, Chenyang Jin, Tao Liu, Wenge Ding*, Fan He*, Yong Xu*. "Bioinspired hydrogel microspheres enhance nucleus pulposus regeneration through N-cadherin interaction and extracellular matrix mimicry." Journal of Controlled Release (2025):113771. (Last corresponding author; IF = 10.8; Category: Zone I)

[4] Xin Tian, Chen Yangjin, Yan Miao, Hao Liu, Xi Chen, Wenge Ding*, Fan He*, Yong Xu*. Dynamic dual-network hydrogel microspheres for enhanced nucleus pulposus regeneration via extracellular matrix mimicry. Composites Part B: Engineering (2025).112715. (Last corresponding author; IF = 12.4; Category: Zone I)

[5] Yesheng Jin, Shuqing Lv, Nanning Lv, Yixue Huanga, Jia Wang, Yun Xiao, Xinfeng Zhou, Yanxia Ma, Gang Zhao*, Fan He*, Yong Xu*. Multi-scale biomimetic fusion construction of a cerium-ion hydrogel scaffold for promoting repair of osteoporotic bone defects. Journal of Orthopaedic Translation 55 (2025):172–191 (Last corresponding author; IF = 7.8; Category: Zone I).

[6] Yang Liu, Yijian Zhang, Chenqi Yu, Xiaowei Xia, Kang Kang, Yubin Wu, Yaoge Deng, Jianfeng Yu, Mingzhuang Hou, Zhiwen Luo, Huilin Yang*, Yong Xu*, Xuesong Zhu*: "Three birds with one stone": Modified organic diselenide hydrogel microspheres for the treatment of osteoarthritis. Nature Communications (2026). (Co-corresponding author; IF = 15.7; Category: Zone I)

Published other papers as first or corresponding author (including co-authors) in the past five years:

[7] Can Huang, Lanlan Dong, Baohua Zhao, Yifei Lu, Shurun Huang, Zhiqiang Yuan, Gaoxing Luo*, Yong Xu*, Wei Qian*. Anti-inflammatory hydrogel dressings and skin wound healing. Clinical and Translational Medicine, 12(11), e1094 (2022). (Co-corresponding author; IF = 10.6; Category: Zone I).

[8] X Xia, Y Liu, Y Lu, J Liu, Y Deng, Y Wu, M Hou, F He, H Yang, Y Xu*, Y Zhang*, X Zhu*. Restoring Mitochondrial Apoptosis/Mitophagy Balance via SIRT3-Energized and Microenvironment-Modulated Hydrogel Microspheres to Prevent Osteoarthritis. Advanced Healthcare Materials (2023):2302475 (Co-corresponding author; IF = 11.092; Category: Zone I).

[9] X Hu, Xin Tian, C Yang, F Ling, H Liu, X Zhu, M Pei, H Yang, T Liu, Y Xu*, F He*. Melatonin-loaded self-healing hydrogel targets mitochondrial energy metabolism and promotes annulus fibrosus regeneration. Materials Today Bio (2023):100811. (Co-corresponding authors; IF = 8.2; Category: Zone I)

[10] Can Huang, Lanlan Dong, Baohua Zhao, Shurun Huang, Yifei Lu, Xiaorong Zhang, Xiaohong Hu, Yong Huang, Weifeng He, Yong Xu*, Wei Qian* & Gaoxing Luo*. A tunable sulfated alginate-based hydrogel platform with enhanced anti-inflammatory and antioxidant properties for promoting burn wound healing. Journal of Nanobiotechnology 21.1 (2023):387. (Co-corresponding author; Impact Factor = 10.2; Category: Zone I).

[11] Zhangzhe Zhou, Yang Liu, Wenjing Li, Zhijian Zhao, Xiaowei Xia, Junlin Liu, Yaoge Deng, Yubin Wu, Xiangqiang Pan, Fan He, Huilin Yang, Weihong Lu*, Yong Xu*, Xuesong Zhu*. A self-adaptive biomimetic periosteum utilizing nitric oxide release to enhance angiogenesis in bone defect regeneration [J]. Advanced Healthcare Materials, 2023:2302153. (Co-corresponding author; Impact Factor = 10; Category: Zone I).

[12] H. Liu, X. Tian, C. Jin, Y. Li, X. Zhu, M. Pei, T. Liu, H. Yang*, Y. Xu*, F. He*. Delivery of cells via ECM-mimetic hydrogel microspheres to promote the reconstruction of the lumbar nucleus pulposus in rats. Chemical Engineering Journal (2024):150212 (Co-corresponding author; Impact Factor = 15.1; Category: Zone I). J. Liu, Z. Zhou, M. Hou, X. Xia, Y. Liu, Z. Zhao, Y. Wu, Y. Deng, Y. Zhang, F. He*, Y. Xu*, X. Zhu*. Capture of cerium ions via hydrogel microspheres promotes vascularization for bone regeneration [J]. Materials Today Bio, 2024,25:100956 (Co-corresponding author; Impact Factor = 8.2). Partition: Zone I)

[13] Xiaoyang Ge, Chengyue Wang, Guanyu Yang, Dimulati Maimaiti, Mingzhuang Hou, Hao Liu, Huilin Yang, Xi Chen, Yong Xu*, Fan He*. Melatonin enhances mitochondrial energy metabolism and promotes vascularized skeletal muscle regeneration in a volumetric muscle loss model [J]. Free Radical Biology and Medicine, 2024. (Co-corresponding author; IF = 7.4; Category: Zone I)

[14] B Zhang, Z Zhou, Y Zhang, Y Miu, C Jin, W Ding, G Zhao, Yong Xu*. A Sugary Solution: Utilizing Polysaccharide-Based Materials for Osteoporosis Treatment. Carbohydrate Polymers (2024):122549. (Last corresponding author; IF = 10.7; Category: Zone I)

[15] J Chen, X Zhou, Y Li, T Liu, W Ding, F He, Yong Xu*. Transforming Osteoarthritis Treatment: Embracing Hydrogel Microspheres. ACS Materials Letters 6.8 (2024):3862–3882. (Last corresponding author; IF = 9.6; Category: Zone I)

[16] M Hou, Y Deng, N Lv, Y Wu, Y Zhu, Y Zhang, Y Liu, X Xia, C Yu, J Yu, F He*, Yong Xu*, X Zhu*. Cyclic amplification of the remodeling bone regeneration process via cerium-energy-enhanced spinning hydrogel biomembrane for rescuing osteoporotic bone defects. Chemical Engineering Journal 492 (2024):152262. (Co-corresponding author; IF = 15.1; Category: Zone I)

[17] Rebecca Rothe#, Yong Xu#, Johanna Wodtke, Florian Brandt, Sebastian Meister, Markus Laube, Pier-Luigi Lollini, Yixin Zhang, Jens Pietzsch, Sandra Hauser. Programmable release of chemotherapeutic agents from ferrocene-based injectable hydrogels inhibits melanoma growth. Advanced Healthcare Materials (2024):2400265. (Co-first author; IF = 10; Category: Zone I)

[18] Xiaozhen Liu, Zhuozhuo Ren, Xuli Meng* & Yong Xu*. Substrate topography regulates the secretion of extracellular matrix components by bone marrow-derived mesenchymal stem cells. Journal of Science: Advanced Materials and Devices, 100437. (2022). (Corresponding author; IF = 7.382; Category: Zone II)

[19] Wei He, Xin Tian, Quan Zhou, Jiaheng Lv, Yangfeng Li, Chenyang Jin, Hao Liu, Huiling Yang, Yong Xu*, Fan He* & Tao Liu*: Selenium nanoparticles ameliorate lumbar disc degeneration by restoring GPX1-mediated redox homeostasis and mitochondrial function in nucleus pulposus cells. J Nanobiotechnol 22,634 (2024) (Co-corresponding authors; IF = 10.6; Category: Zone I).

[20] authors: Imulati Maimaiti, Xiaoyang Ge, Chengyue Wang, Jinuo Liu, Guanyu Yang, Dachuan Zhang, Yong Xu*, Fan He*, Xi Chen*. Cryogels mimicking the extracellular matrix, composed of methacrylated fucoidan, enhance vascularized skeletal muscle regeneration following volumetric muscle loss. International Journal of Biological Macromolecules 283 (2024):137122. (Co-corresponding author; IF = 7.7; Category: Zone I)

[21] X Wang, Y Huang, Y Yang, X Tian, Y Jin, W Jiang, H He*, Y Xu*, Y Liu*. Polysaccharide-based biomaterials for regenerative therapy in intervertebral disc degeneration. Materials Today Bio (2024):101395. (Co-corresponding authors; IF = 8.7; Category: Zone I)

[22] Zhiyang Ren, Shuhan Tang, Jia Wang, Shuqing Lv, Kai Zheng*, Yong Xu*, Ke Li*. Bioactive Glasses: Advancing Skin Tissue Repair Through Multifunctional Mechanisms and Innovations. Biomaterials Research 29 (2025):0134. (Co-corresponding author; IF = 8.1; Category: Zone I)

[23] Q Hou, X He, M Guo, X Li, Z Zhang, X Xu, Y Xu*, Q Shi*, Y Han*. Enhanced hemostatic efficacy of cryogel combined with copper-ion-loaded mesoporous bioactive glasses for acute and persistent bleeding. Journal of Nanobiotechnology 23(1) (2025):1–19. (Co-corresponding authors; IF = 10.6; Category: Zone I).

[24] X Zhou, X Tian, J Chen, Y Li, N Lv, H Liu, T Liu, H Yang, X Chen*, Y Xu*, F He*. Youthful Stem Cell Microenvironments: Rejuvenating Aged Bone Repair Through Mitochondrial Homeostasis Remodeling. Advanced Science (2025):2409644. (Co-corresponding author; IF = 14.44; Category: Zone I)

[25] S Zhao, X Hu, Y Zhao, Y Zhang, Y Jin, F Hua*, Y Xu*, W Ding*. Hydrogel-based therapies for diabetic foot ulcers: recent developments and clinical implications. Burns & Trauma 13 (2025): tkae084. (Co-corresponding author; IF = 6.3; Category: Zone I)

[26] Can Huang, Yijie Liu, Baohua Zhao, Mengjun He, Shurun Huang, Lanlan Dong, Yifei Lu, Guangyun Hu, Xiaoqing Zhou, Yong Xu*, Wei Qian*, Gaoxing Luo*. A dual-response hydrogel system coordinating immunomodulation and tissue repair to promote healing of infected burn wounds. ACS Materials Letters, 2025,7: 489–499. (Co-corresponding authors; IF = 9.9; Category: Zone I)

[27] Junqi Dai, Li Ni, Chenyang Jin, Xin Tian, Yujie Shen, Yan Miao, Yong Xu*, Fan He*, Huilin Yang*. Esterase-responsive kartogenin composite hydrogel microspheres enhance nucleus pulposus regeneration in intervertebral disc degeneration. Acta Biomaterialia 2025,198(1):131150. (Co-corresponding author; IF = 9.4; Category: Zone I)

[28] Feng Ling, Xiayu Hu, Yujie Shen, Xi Chen, Zonglai Qian, Hao Liu*, Yong Xu*, Fan He*. A polysaccharide hydrogel-reinforced nanofibrous composite promotes annulus fibrosus regeneration by regulating mitochondrial antioxidant and metabolic functions. Chemical Engineering Journal (2025),164696. (Co-corresponding author; IF = 13.2; Category: Zone I)

[29] Xu He, Xingzhi Liu, Xinyi Cheng, Can Zhu, Yida Chen, Yi Wang, Yun Zhou, Hao Shen, Huilin Yang, Yong Xu*, Qin Shi*, Junjie Niu*. Bionic bearing-inspired lubricating microspheres with immunomodulatory effects for osteoarthritis therapy. Journal of Nanobiotechnology 23,457 (2025). (Co-corresponding author; IF = 12.6; Category: Zone I)

[30] Liu #, Runqi Wang #, Yong Xu #, Qingyi Liu, Yin Li, Xiangpeng Liu, Hui Shu, Kaige Gao, Xingye Zheng, Yingying Dong, Yijun Wang, Bin Guo, Lei Fu, Bin Zhang, Liang Zhao, Zhihao Jia, Xiaobo Sun. Metformin administration protects against deltoid tendon damage by activating Notch signaling. iMeta (2025) e70074. (Co-first author; IF = 33.2; Category: Zone I).

[31] Jin, Chenyang, Jianan Chen, Yan Miao, Xin Tian, Jia Wang, Fan He*, Yijie Liu*, and Yong Xu*. "Cuttlefish Ink Nanoparticle-Engineered Hydrogel Microspheres Synergistically Attenuate Disc Degeneration Through Antioxidant Defense and Matrix Synthesis Activation." Materials Today Bio (2025):102244. (Last corresponding author; IF = 10.2; Category: Zone I)

[32] Ma, Ruikai, Shuao Zhao, Yesheng Jin, Yinhao Li, Huxin Tang, Mingyang Hu, Xinyu Hu*, Yong Xu*, and Wenge Ding*. "Advancing biomaterial innovation for tissue engineering through microbial synthetic biology: A review." International Journal of Biological Macromolecules (2025):146771. (Co-corresponding authors; Impact Factor = 8.5; Category: Zone II).

[33] Jin, Yesheng, Yixue Huang, Jia Wang, Xinfeng Zhou, Jianan Chen, Wenge Ding*, Zhihao Jia*, and Yong Xu*. "From Injury to Integrity: Tissue Engineering Solutions in Combined Bone Repair and Regeneration and Muscle Repair." Burns & Trauma (2025): tkaf052. (Last corresponding author; IF = 9.6; Category: Zone II)

[34] Xiaoyang Ge, Yesheng Jin, Jingyuan He, Zhihao Jia*, Ying Liu*, Yong Xu*. The extracellular matrix in skeletal muscle injury and atrophy: mechanisms and therapeutic implications. Journal of Orthopaedic Translation (2025),404–418, p. 52. (Last corresponding author; IF = 7.8; Category: Zone I)

[35] Jiaheng Lv, Yujie Shen, Quan Zhou, Wei He, Yulin Chen, Xi Chen, Huilin Yang, Yong Xu*, Fan He*, Tao Liu*. Selenium-functionalized hydrogel microspheres promote nucleus pulposus reconstruction by activating selenoprotein-mediated mitochondrial redox homeostasis and energy metabolism. Biomaterials (2025):123826. (Co-corresponding authors; IF = 12; Category: Zone I)

[36] Yixue Huang, Yilin Yang, Jia Wang, Shuqing Lv, Yesheng Jin, Xinfeng Zhou, Yun Xiao, Shuo Chen*, Tingting Zhu*, Yong Xu*. From Death to Renewal: Apoptotic Bodies as Pioneering Tools in Musculoskeletal System Regeneration. Advanced Healthcare Materials (2025) (Last corresponding author; IF = 9.6; Category: Zone II).

[37] Yantong Li, Jianan Chen, Shuo Chen, Xue Ding, Xinfeng Zhou, Jin Li, Tingting Zhu*, Yong Xu*, Fan He*. Polysaccharide-inspired biomaterials for skeletal muscle regeneration: innovations for treating volumetric muscle loss. Acta Biomaterialia (2025) (Co-corresponding author; IF = 9.6; Category: Zone I).

[38] Shuqing Lv, Jia Wang, Jianan Chen, Yunyuan Yu, Xinying Huang, Gang Zhao*, Xinfeng Zhou* & Yong Xu*. Mesenchymal stem cell-derived extracellular matrix for musculoskeletal tissue regeneration. Commun Biol 9, 147 (2026). (Last corresponding author; IF = 5.4; Category: Zone I)

[39] Huxin Tang, Mingyang Hu, Xinying Huang, Jianan Chen, Yesheng Jin, Shuo Chen*, Ke Li*, Yong Xu*. Harnessing polysaccharide-mediated biomineralization for advanced bone tissue engineering. Materials Today Bio (2026):102846. (Last corresponding author; IF = 10.2; Category: Zone I).

[40] Zhang, Xiongjinfu, Xingzhi Liu, Yi Wang, Can Zhu, Daihui Liu, Yi Zheng, Yixin Zhang, Huilin Yang*, Yong Xu*, and Qin Shi*. "An electrostatic co-assembled extracellular vesicle-infused hydrogel for bone regeneration in aged defects." Biomaterials (2026):124254. (Co-corresponding author; IF = 12; Category: Zone I)

[41] Zhao, Shuao, Yesheng Jin, Zhihao Jia, Rongzhao Gu, Yanxia Ma, Yige Zhang, Yiwen Zhao, Ke Li*, Yong Xu*, and Wenge Ding*. "Self-assembled mesoporous bioglass polyphenol nanozymes for repairing musculoskeletal trauma." Biomaterials (2026):124153. (Co-corresponding author; IF = 12; Category: Zone I)

[42] Zhou, Xiaoqing, Guangyun Hu, Can Huang, Ying Liu, Zhou-rui Ma, Yangguang Lu*, Yong Xu*, and Wei Qian*. "An ultrasmall Prussian blue-integrated cryogel for enhanced ROS scavenging and immunomodulation through cGAS–STING inhibition in wound healing." Materials Today Bio (2026):103056. (Co-corresponding authors; IF = 10.2; Category: Zone I)

Representative publications by the first author (2018–2023):

[43] Yong Xu*, Rebecca Rothe, Dagmar Voigt, Ahmed Sayed, Can Huang, Sandra Hauser, Pao-Wan Lee, Meiying Cui, James P. Saenz, Aldo R. Boccaccini, Kai Zheng*, Jens Pietzsch*, and Yixin Zhang*. A self-assembled dynamic hydrogel system resembling an extracellular matrix with multi-scale structures for cell bioengineering applications. Acta Biomaterialia (2023). (First author & co-corresponding author; Impact Factor: 10.633; Category: Zone I)

[44] Yong Xu*, Michelle Patino Gaillez, Kai Zheng, Dagmar Voigt, Meiying Cui, Thomas Kurth, Lingfei Xiao, Rebecca Rothe, Sandra Hauser, Pao-Wan Lee, Robert Wieduwild, Weilin Lin, Martin Bornhauser, Jens Pietzsch, Aldo R. Boccaccini, and Yixin Zhang*. A Self-Assembled Matrix System for Cell-Bioengineering Applications in Different Dimensions, Scales, and Geometries. Small, 2104758. (2022). (First author & co-corresponding author; IF 15.153; Category: Zone I)

[45] Yong Xu, Panagiotis A. Patsis, Sandra Hauser, Dagmar Voigt, Rebecca Rothe, Markus Gunther, Meiying Cui, Xuegeng Yang, Robert Wieduwild, Kerstin Eckert, Christoph Neinhuis, Teuku Fawzul Akbar, Ivan R. Minev, Jens Pietzsch*, and Yixin Zhang*. Cytocompatible, injectable, and electroconductive soft adhesives with a hybrid covalent/noncovalent dynamic network. Advanced Science, 6(15),1802077 (2019). (First author; IF 17.521; Category: Zone I)

[46] Yong Xu, Michelle Patino Gaillez, Rebecca Rothe, Sandra Hauser, Dagmar Voigt, Jens Pietzsch*, Yixin Zhang*. Conductive hydrogels with dynamic reversible networks for biomedical applications. Advanced Healthcare Materials, 10(11),2100012 (2021). (First author; IF 11.092; Category: Zone I)

[47] Rebecca Rothe#, Yong Xu#, Alvin Kuriakose Thomas, Sebastian Meister, Yixin Zhang, Jens Pietzsch, Sandra Hauser. A modular, injectable, non-covalently assembled hydrogel system exhibits broad-spectrum tunable degradability for controlled release and tissue integration. Biomaterials, 269,120637 (2021). (Co-first authors; IF 15.304; Category: Zone I)

[48] Yong Xu, Meiying Cui, Panagiotis A. Patsis, Markus Gunther, Xuegeng Yang, Kerstin Eckert, and Yixin Zhang*. A reversibly assembled electroconductive hydrogel developed through host-guest interactions for 3D cell culture. ACS Applied Materials & Interfaces, 11(8):7715–7724 (2019). (First author; Impact Factor: 10.383; Category: Zone II)

[49] Yong Xu, Xuegeng Yang, Alvin Kuriakose Thomas, Panagiotis A. Patsis, Thomas Kurth, Martin Krater, Kerstin Eckert, Martin Bornhauser, and Yixin Zhang. Noncovalently assembled electroconductive hydrogel. ACS Applied Materials & Interfaces, 10(17),14418–14425 (2018). (First author; Impact Factor: 10.383; Category: Zone II)

Authoritative Patent Invention

1. Zhang YX, Xu Y, Thomas A K. Non-covalently assembled conductive hydrogel with modular structural motifs, dynamic network, and seamless interface with cells. PCT International Patent (Grant Nos.: EP3395327B1 & US11166907B2) granted in the European Union and United States.

2. Gong Yihong; Xu Yong; Zhang Xujie; He Fan; Li Yan; Jiang Qing; A electrospun nanofiber-extracellular matrix composite material and its preparation method and application, April 20,2016, China, ZL201410116021.X granted

3. Gong Yihong; Xu Yong; He Fan; Li Yan; Jiang Qing. A type of natural gel scaffold material for tissue engineering and its preparation method and application. China, May 20,2015, ZL201310494942.5. Authorized.

4. Xu Yong (First Inventor): A collagen protein from sheep spinal nucleus pulposus and its extraction method, granted on March 19,2024, China, ZL 202310989039.X

5. Xu Yong (First Inventor): A collagen from the annulus fibrosus of sheep spine and its extraction method and application, March 19,2024, China, ZL202310985391.6 granted

6. Xu Yong (First Inventor): A preparation method for a hydrogel-electrospun membrane bilayer hybrid scaffold, October 28,2024, China, CN202410799045.3 granted

7. Xu Yong (First Inventor) A method for preparing extracellular matrix hydrogel microspheres, 2024-09-23, China, CN118356529A granted

8. Xu Yong (First Inventor): A self-assembling bioglass hydrogel, its preparation method and applications, 2025-4-18, China, ZL 2022 1 1674655.8 granted

9. Xu Yong (First Inventor): A squid ink hydrogel microsphere, its preparation method, and applications, 2025-03-30. ZL202411857114.8

10. Yong Xu. Extracellular Matrix Hydrogel Microsphere, and Its Preparation Method and Application. PCT International Patent (Grant No.: US12447234B1) granted in the United States.

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